Expanding roles of de novo lipogenesis in breast cancer
… (PR) expression and confers a more favorable prognosis in part … and worst overall survival
rate among all breast cancer subtypes [… Furthermore, epithelial breast cancer cells with high …
rate among all breast cancer subtypes [… Furthermore, epithelial breast cancer cells with high …
Aberrant lipid metabolism as an emerging therapeutic strategy to target cancer stem cells
… markers in breast cancer stem-like cells, mammospheres, … in lipogenic enzymes that contribute
to progression of cancer, … CD36-enriched, conferring increased survival advantage and …
to progression of cancer, … CD36-enriched, conferring increased survival advantage and …
Targeting autophagy and lipid metabolism in cancer stem cells
B Chakravarti, JA Siddiqui, RA Sinha, S Raza - Biochemical pharmacology, 2023 - Elsevier
… Cancer cells use increased lipogenesis to fulfill their heightened … these stem-like cells
showed increased dependence on … stemness and confers survival advantage under stressful …
showed increased dependence on … stemness and confers survival advantage under stressful …
[HTML][HTML] Metabolic targeting of cancer stem cells
A Mukha, A Dubrovska - Frontiers in Oncology, 2020 - frontiersin.org
… Many of these pathways confer cell adaptation to the … ; interesting that pancreatic CSCs fuelled
their lipogenesis via enhanced … showing the benefit of a ketogenic diet for cancer patients, …
their lipogenesis via enhanced … showing the benefit of a ketogenic diet for cancer patients, …
[HTML][HTML] Bioactive lipids in cancer stem cells
… Breast CSCs have shown elevated levels of lipogenic genes … stimulates hepatocellular
carcinoma stem-like cells by … mitochondria, which confer survival to cancer cells when metabolic …
carcinoma stem-like cells by … mitochondria, which confer survival to cancer cells when metabolic …
Oxidative stress regulation and related metabolic pathways in epithelial–mesenchymal transition of breast cancer stem cells
… Given the elevated level of lipogenesis in cancer cells, it can … the EMT process while leaving
the initial tumor site. It is well … corresponding tumor cells, breast cancer stem-like cells exhibit …
the initial tumor site. It is well … corresponding tumor cells, breast cancer stem-like cells exhibit …
Disruption of cancer metabolic SREBP1/miR-142-5p suppresses epithelial–mesenchymal transition and stemness in esophageal carcinoma
CM Huang, CS Huang, TN Hsu, MS Huang, IH Fong… - Cells, 2019 - mdpi.com
… of SREBP1 resulted in increased levels of lipogenic genes, … lipogenesis and sphere formation
in MCF10A stem-like cells [… promotes the invasive phenotype of breast cancer cells [27]. …
in MCF10A stem-like cells [… promotes the invasive phenotype of breast cancer cells [27]. …
Lipid metabolism of cancer stem cells
H Liu, Z Zhang, L Song, J Gao… - Oncology Letters, 2022 - spandidos-publications.com
… an increase in fatty acid (FA) uptake, de novo lipogenesis, … pathways are also critical to
cancer cell survival, such as lipid … , tumor-initiation properties and generation of stem-like TICs, …
cancer cell survival, such as lipid … , tumor-initiation properties and generation of stem-like TICs, …
LncRNA IPW inhibits growth of ductal carcinoma in situ by downregulating ID2 through miR-29c
… As our group and others have previously demonstrated the role of cancer stem-like cells (…
, we found that high IPW expression is correlated with significantly longer overall survival of …
, we found that high IPW expression is correlated with significantly longer overall survival of …
Targeting glucose metabolism to overcome resistance to anticancer chemotherapy in breast cancer
… -negative breast cancers (TNBC), do not benefit from hormone… were linked to an increased
level of lipogenesis, marked by … confers a high degree of metabolic heterogeneity in various …
level of lipogenesis, marked by … confers a high degree of metabolic heterogeneity in various …